Prognostic value of different cardiac MRI parameters for the diagnosis of myocarditis

Results 209 cases were reviewed; mean age 47 and 58% men. 74 (35%) patients were diagnosed with myocarditis based on CMR. The number of patients with 0, 1, 2 and 3 criteria positive was 70 (33%), 65 (31%), 49 (23%) and 25 (12%) respectively. Age, gender, diabetes, hypertension, smoking, CAD, prior CHF and CRI were similar among all groups. There was a trend for higher prevalence of NYHA class III or IV in myocarditis patients (17% vs 7.8 %; P=0.05). Baseline LVEF was 48.44±18 by TTE and 46±21 by CMR with no significant differences between groups. Mean increase in LVEF at 6 months by TTE for patients with 0, 1, 2 and 3 criteria positive was 5±10, 13±11, 11±10 and 6±12 (P=0.147). Mean change in LVEF for three myocarditis groups based on abnormal T1 and T2, T1 and DE or T2 and DE was 10±9, 10±7 and 7±9 (P=0.39). MACE was achieved in 20 (37%) patients with myocarditis and 21 (23%) patients without the diagnosis (P=0.078). The rate of MACE in patients with 0, 1, 2 and 3 positive criteria was 11 (22%), 10 (25%), 13 (37%) and 7 (37%) (P=0.127 and 0.21 for 0 vs 2 and 0 vs 3 criteria). The three groups based on positive T1 and T2, T1 and DE or T2 and DE had MACE rates of 3 (23%), 5 (38%) and 5 (38%) with no significant differences on pairwise comparisons.